Bupropion is an antidepressant that stimulates noradrenaline, dopamine, and serotonin. This medication is not FDA-approved for weight loss, but can be used to decrease appetite. It can promote a boost of energy and mood

Topiramate is a medication traditionally used for seizure disorders, migraines and certain psychiatric conditions. It can be used off-label for appetite suppression.

Naltrexone is used for opioid and alcohol use disorders by preventing the euphoric effects. It has been shown to also block the rewarding effects of eating food. 

Methylcobalamin is a form of B12 that can boost energy and metabolism of fats.

Oxytocin is a hormone that plays an important role in social interaction, sexual reproduction and trust (also known as the “love hormone”). Studies have shown that it can influence the reward center of the brain leading to decreased motivation to eat high-calorie foods.